The Future of Dermatology
Join Dr. Faranak Kamangar, MD, every week as she chats with various guests about the future of dermatology. Each week, Dr. Kamangar and her guests cover topics from psoriasis, to eczema, to skin care, to AI, and more. Whether you’re a doctor or a patient, these episodes provide valuable information about your skin and how to navigate the world of dermatology.
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Episodes
Tuesday Apr 02, 2024
Tuesday Apr 02, 2024
Summary
In this episode of the Future of Dermatology podcast, Dr. Farah Kamangar and Dr. Tina Bhutani discuss the mechanism of action of aryl hydrocarbon receptors (AHR) and its potential in dermatology. They explore the history of AHR and its connection to coal tar, as well as its role in inflammation, antioxidant activity, and metabolism. They also touch on the importance of considering the impact of circadian rhythms and sleep on skin health. The conversation highlights the potential of AHR-targeted therapies in achieving longer remissions and the need to view psoriasis patients as a whole, addressing comorbidities and environmental factors. The episode concludes with a discussion on the future of dermatology, including the possibility of directly targeting resident memory T cells and the further exploration of AHR mechanisms.
This episode is sponsored by an educational grant from the company Dermavant.
Takeaways
Aryl hydrocarbon receptors (AHR) have a complex mechanism of action and can have anti-inflammatory, antioxidant, and metabolic effects.
AHR-targeted therapies, such as tofacitinib, have shown promise in achieving longer remissions in psoriasis patients.
Considering the impact of circadian rhythms and sleep on skin health is important, as sleep loss can increase inflammation and affect skin diseases.
Psoriasis patients should be viewed as a whole, addressing comorbidities and environmental factors.
The future of dermatology may involve directly targeting resident memory T cells and further exploring the mechanisms of AHR.
AHR-targeted therapies may offer new possibilities for treating inflammatory skin diseases and achieving longer remissions.
Chapters
00:00 Introduction
02:24 Understanding the Mechanism of Action of Aryl Hydrocarbon Receptors
09:07 The Impact of Circadian Rhythms and Sleep on Skin Health
12:43 Viewing Psoriasis Patients as a Whole
16:39 The Potential of AHR-Targeted Therapies in Achieving Longer Remissions
22:35 Exploring the Mechanisms of Aryl Hydrocarbon Receptors
Wednesday Mar 27, 2024
Wednesday Mar 27, 2024
Summary
In this follow up episode, Dr. Wilson Liao shares insights on the benefits of a research year for medical students and offers advice on transitioning back to medical school. He and SFDS Med Student, Chandler Johnson, also discuss the future of dermatology and the role of team science in advancing research.
Takeaways
A research year provides medical students with valuable skills and insights into the field of dermatology.
Transitioning back to medical school requires a clinical refresher and practicing essential clinical skills.
Team science and collaboration are key to advancing dermatology research and finding better treatments for patients.
Tuesday Mar 26, 2024
Tuesday Mar 26, 2024
Summary
In this episode, Dr. Wilson Liao discusses the genetics and environmental triggers of psoriasis. He highlights the significant progress made in identifying psoriasis genes and how they relate to the different types and severity of psoriasis. Dr. Liao also explores the connection between psoriasis genes and therapeutic response, as well as the potential for precision medicine in psoriasis treatment. The conversation delves into the evolutionary persistence of psoriasis and its survival advantage in fighting off viruses. The role of environmental triggers, such as obesity, diet, and smoking, is also examined. Additionally, Dr. Liao and Chandler Johnson discuss their current research studies, including the Skin Tracker Project and capillary blood testing. In this conversation, Dr. Wilson Liao and Chandler Johnson discuss various research projects and clinical trials in dermatology. They explore the use of RNA and proteins in research, the importance of studying multiple aspects of autoimmune disease, and ongoing psoriasis survey studies. They also delve into the impact of menopause on psoriasis and the relationship between sleep and psoriasis.
Takeaways
Significant progress has been made in identifying over 100 psoriasis genes, which has led to a better understanding of the different types and severity of psoriasis.
Genetic testing can help predict therapeutic response and guide treatment decisions, with the potential for precision medicine in psoriasis.
Psoriasis genes may have persisted evolutionarily due to their role in fighting off viruses, as seen in the similarities between psoriasis patients and HIV non-progressors.
Environmental triggers, such as obesity, diet, and smoking, can contribute to the development and severity of psoriasis.
Current research studies, including the Skin Tracker Project and capillary blood testing, aim to improve accessibility to clinical trials and provide insights into the molecular mechanisms of psoriasis. Research in dermatology involves studying RNA, proteins, and multiple aspects of autoimmune disease.
Psoriasis survey studies are being conducted to explore the impact of menopause and sleep on psoriasis.
Help us understand how psoriasis affects you
Help Us Understand More About Sleep and Psoriasis Are you interested in helping researchers understand how psoriasis and sleep are related?
Please consider taking our paid online survey. Recruiting both individuals with and without psoriasis. https://redcap.ucsf.edu/surveys/?s=RLFR379LNL4RFTTF
Help Us Understand About Menopause and Psoriasis Are you interested in helping researchers understand how psoriasis and menopause are related?
Please consider taking our paid online survey. Recruiting post-menopausal women with psoriasis. https://redcap.ucsf.edu/surveys/?s=JYTNX3XKDC84J3DX
Tuesday Mar 19, 2024
Tuesday Mar 19, 2024
Summary:
Dr. Keira Barr, MD, shares her non-traditional journey in dermatology and her focus on the mind-body connection in skin health. She discusses the harmful phrase "anti-aging" and the need to shift the conversation to a more positive and empowering approach. Dr. Barr also highlights the challenges and complexities of cosmetic dermatology consultations and the importance of addressing the psychological aspects of these procedures. She emphasizes the connection between mental health and skin health, particularly in relation to stress and trauma. Dr. Barr advocates for a more holistic and personalized approach to dermatology, incorporating mind-body techniques and personalized medicine. In this conversation, Dr. Keira Barr discusses the importance of skin health and provides insights into common skin conditions, prevention and treatment methods, and the role of skin care products. She also emphasizes the importance of skin cancer awareness and highlights the connection between skin health and overall well-being.
Takeaways:
The phrase 'anti-aging' is harmful and should be replaced with a more positive and empowering approach to aging.
Cosmetic dermatology consultations require addressing the psychological aspects of the procedures and understanding the motivations behind them.
The mind-body connection is crucial in dermatology, as stress and trauma can impact skin health.
Physicians need to prioritize building a connection with their patients and addressing their mental and emotional well-being.
The future of dermatology lies in a more holistic and personalized approach, incorporating mind-body techniques and personalized medicine. Maintaining healthy skin is essential for overall well-being.
Common skin conditions can be effectively prevented and treated with proper care. Choosing the right skin care products is crucial for maintaining skin health.
Regular skin cancer screenings and awareness are important for early detection and treatment.
Skin health is interconnected with overall physical and mental well-being.
Learn more from Dr. Barr at:
Website: drkeirabarr.com
Skincare Quiz: yourskincarequiz.com
Podcast: The Skinny Dipping Rx: https://podcasts.apple.com/us/podcast/the-skinny-dipping-rx/id1635601527
Instagram: @drkeirabarr
Tuesday Mar 12, 2024
Tuesday Mar 12, 2024
Summary
In this episode, Dr. Farah Kamangar discusses the effects of alcohol on the skin. She highlights the importance of considering alcohol consumption as a potential factor in dermatological conditions such as rosacea, eczema, and psoriasis. Dr. Kamangar also explains the guidelines for alcohol consumption and emphasizes the need to follow them to maintain skin health. Additionally, she explores the impact of alcohol on the immune system and its contribution to skin aging.
Takeaways
Alcohol consumption can lead to various skin conditions, including rosacea, eczema, and psoriasis.
It is important to understand the guidelines for alcohol consumption and follow them to maintain skin health.
Excessive alcohol intake can weaken the immune system and increase the risk of skin cancers.
Alcohol can contribute to premature aging of the skin.
Chapters
00:00
Introduction
00:32
Alcohol and its effects on the skin
03:14
Guidelines for alcohol consumption
04:10
Effects of alcohol on the skin
05:02
Alcohol and rosacea
06:28
Alcohol and other skin conditions
08:23
Alcohol and immune system
09:19
Alcohol and aging
09:49
Conclusion
Tuesday Mar 05, 2024
Tuesday Mar 05, 2024
Summary
In this episode of the Future of Dermatology Podcast, Dr. Faranak Kamangar discusses the shift from anti-aging to longevity in the field of dermatology. She explores the changing beauty standards and the desire to look more youthful and functionally enhanced. Dr. Kamangar also delves into the causes of aging, such as the fibroblast collapse theory, and the importance of behavioral changes and topical treatments for anti-aging. She highlights the role of retinoids in collagen production and introduces emerging therapies for anti-aging, including mTOR inhibitors and senolytics. The episode concludes with a discussion on the controversies surrounding the diagnosis of aging.
Takeaways
The focus in dermatology has shifted from anti-aging to longevity and health span.
Behavioral changes, such as sun protection and stress reduction, are important for anti-aging.
Topical treatments like retinoids can stimulate collagen production and improve skin health.
Emerging therapies, including mTOR inhibitors and senolytics, show promise in anti-aging research.
Tuesday Feb 27, 2024
Tuesday Feb 27, 2024
This podcast kicks off our anti-aging segment starting with Dr. Azadeh Shirazi, MD, FAAD, from More Than a Pretty Face Podcast, as she discusses her background, journey, and current practice in dermatology. Dr. Shirazi emphasizes the importance of social media and online education in connecting with patients and providing valuable information. She also shares her experience transitioning from a large corporate practice to opening her own private practice. She highlights the benefits of having a personalized, boutique practice and the challenges she has faced. Additionally, Dr. Shirazi talks about the creation of her skincare line and the comprehensive approach she takes in formulating her products.
Learn more at: https://azimdskincare.com/ Listen to Dr. Azi's podcast, More Than a Pretty Face, at https://morethanaprettyface.libsyn.com/
Tuesday Feb 20, 2024
Tuesday Feb 20, 2024
In our second Ask Me Anything, host Payton Smith asks Dr. Faranak Kamangar questions around patch testing for contact allergies, the difference between patch testing done by dermatologists and allergists, the use of oral minoxidil for hair loss, treatment options for chronic itch, the difference between emollients and lotions, the effectiveness of argireline and tretinoin for wrinkle reduction, the frequency and safety of micro-needling, and the treatment of scars.
Check out our shorts for the quick answers then come back to this podcast to learn more! https://www.youtube.com/@TheFutureofDermatology/shorts